KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NTRK1
All Species:
20.61
Human Site:
S475
Identified Species:
45.33
UniProt:
P04629
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04629
NP_001007793.1
796
87497
S475
F
M
T
L
G
G
S
S
L
S
P
T
E
G
K
Chimpanzee
Pan troglodytes
Q5IS37
825
92786
T490
H
I
N
H
G
I
T
T
P
S
S
L
D
A
G
Rhesus Macaque
Macaca mulatta
XP_001114243
830
91103
S509
F
M
T
L
G
G
S
S
L
S
P
T
E
G
K
Dog
Lupus familis
XP_851619
796
87180
S475
F
M
T
L
G
G
S
S
L
S
P
T
E
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3UFB7
799
87720
S478
F
M
T
L
G
G
S
S
L
S
P
T
E
G
K
Rat
Rattus norvegicus
P35739
799
87850
S478
F
M
T
L
G
G
S
S
L
S
P
T
E
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509236
908
101917
Q586
G
G
P
W
I
S
G
Q
C
S
P
T
E
K
K
Chicken
Gallus gallus
Q91009
778
87320
P458
F
M
T
L
G
S
S
P
V
S
S
T
E
S
K
Frog
Xenopus laevis
O73798
1358
153845
A980
N
P
E
Y
F
S
A
A
E
M
Y
V
P
D
K
Zebra Danio
Brachydanio rerio
XP_697246
619
70072
T359
C
A
N
L
C
P
D
T
D
K
M
L
V
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24488
685
78124
E411
H
F
T
L
Q
D
V
E
F
L
E
E
L
G
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.4
87.5
91.2
N.A.
86.3
85.9
N.A.
45.1
62.1
21.7
47.7
N.A.
27.2
N.A.
N.A.
N.A.
Protein Similarity:
100
63.8
89.7
93.7
N.A.
90.9
90.9
N.A.
58.7
72.4
34.3
59.6
N.A.
43.5
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
33.3
66.6
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
33.3
73.3
20
13.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
10
10
0
0
0
0
0
19
0
% A
% Cys:
10
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
0
10
0
0
0
10
10
0
% D
% Glu:
0
0
10
0
0
0
0
10
10
0
10
10
64
0
10
% E
% Phe:
55
10
0
0
10
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
64
46
10
0
0
0
0
0
0
55
10
% G
% His:
19
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
73
% K
% Leu:
0
0
0
73
0
0
0
0
46
10
0
19
10
0
0
% L
% Met:
0
55
0
0
0
0
0
0
0
10
10
0
0
0
0
% M
% Asn:
10
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
0
0
10
0
10
10
0
55
0
10
0
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
28
55
46
0
73
19
0
0
10
0
% S
% Thr:
0
0
64
0
0
0
10
19
0
0
0
64
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
10
0
0
10
10
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _